Publications by authors named "R D Husain"
Background: Methicillin-resistant (MRSA) is a significant burden globally, particularly in the Arabian Gulf region. The United Arab Emirates (UAE) has experienced rising MRSA prevalence, with increasing diversity in the clonal complexes (CCs) identified. The COVID-19 pandemic, with its increased hospitalization rates and antibiotic use, may have further influenced MRSA's genetic evolution and epidemiology in the country.
View Article and Find Full Text PDFBackground: Real-world data on gene addition therapy (GAT) with onasemnogene abeparvovec (OA), including all age groups and with or without symptoms of the disease before treatment are needed to provide families with evidence-based advice and realistic therapeutic goals. Aim of this study is therefore a population-based analysis of all patients with SMA treated with OA across Germany, Austria and Switzerland (D-A-CH).
Methods: This observational study included individuals with Spinal Muscular Atrophy (SMA) treated with OA in 29 specialized neuromuscular centers in the D-A-CH-region.
Introduction: Xia-Gibbs syndrome (XGS) is a rare syndromic disorder characterized by developmental delay with intellectual disability, muscular hypotonia, brain anomalies, and nonspecific dysmorphic features. Different heterozygous variants in have been reported as causal for XGS, comprising mainly stop-gain and frameshift events, but also missense variants, deletions, and a duplication of the locus.
Case Presentation: We hereby report 2 patients with clinical features of XGS.
Long-term Outcomes of Combined Phacotrabeculectomy Surgery in a Singapore Tertiary Hospital.
Asia Pac J Ophthalmol (Phila)
October 2024
Purpose: To describe the long-term outcomes of phacotrabeculectomy from a tertiary glaucoma service in Singapore.
Design: Retrospective case series.
Methods: Seven hundred ninety-six eyes of 698 patients who underwent phacotrabeculectomy surgery at the Singapore National Eye Centre between 2005 and 2007 with a minimum follow-up of three years were included.
Article Synopsis
- - The study aims to evaluate the reliability and consistency of a new hyperparallel optical coherence tomography (HP-OCT) system for assessing angle closure in the eye, comparing it with the existing swept-source OCT (SS-OCT) and gonioscopy methods.
- - Conducted on phakic subjects over 40 years old with no significant eye conditions, the research found that HP-OCT had excellent reproducibility and good agreement with both SS-OCT and gonioscopy for detecting angle closure.
- - The findings suggest that HP-OCT not only excels in angle closure assessment but also uniquely visualizes important eye structures, potentially enhancing clinical research on fluid drainage in the eye.