Performance of Claims-Based Algorithms for Adherence to Positive Airway Pressure Therapy in Commercially Insured Patients With OSA.

Background: Positive airway pressure (PAP) therapy is first-line therapy for OSA, but consistent use is required for it to be effective. Previous studies have used Medicare fee-for-service claims data (eg, device, equipment charges) as a proxy for PAP adherence to assess its effects. However, this approach has not been validated in a US commercially insured population, where coverage rules are not standardized.

Depression and comorbid obstructive sleep apnea: Association between positive airway pressure adherence, occurrence of self-harm events, healthcare resource utilization, and costs.

Objective: Previous studies have shown that treatment of obstructive sleep apnea (OSA) with positive airway pressure (PAP) therapy in patients with depression may improve depression symptoms and response to antidepressant therapy. We investigated the association between PAP therapy adherence, self-harm events, healthcare resource utilization (HCRU), and costs over 2 years in a national sample of patients with pre-existing depression and newly diagnosed comorbid OSA.

Methods: Administrative claims data were linked to objective PAP therapy usage.

THE IMMEDIATE EFFECTS OF A TOTAL MOTION RELEASE® WARM-UP ON ACTIVE ROTATIONAL HIP RANGE OF MOTION IN OVERHEAD ATHLETES.

Background: Reductions in hip range of motion (ROM) correlate with lower extremity injury and alterations in shoulder mechanics in overhead athletes. Such shifts in kinetic-chain dynamics may lead to additional stresses at common injury sites of the upper and lower extremities. Researchers have suggested that Total Motion Release (TMR) increases shoulder ROM more effectively than traditional warm-up methods.

A Luciferase Immunoprecipitation System (LIPS) assay for profiling human norovirus antibodies.

A luciferase immunoprecipitation systems (LIPS) assay was developed to define the antigenic specificity and titer of antibodies directed against human norovirus (HuNoV). Recombinant proteins, expressed by plasmid constructs encoding Renilla luciferase (Ruc) fused to the full-length HuNoV major capsid protein (VP1) (Ruc-antigen), were generated for ten HuNoV strains. In addition, subdomain constructs Ruc-Shell (S) and Ruc-Protruding (P) were engineered for a representative GII.

On the use of non-negative matrix factorisation to characterise wastewater from dairy processing plants.

A portable field spectrometer was used to record the time-resolved ultraviolet/visible (UV/Vis) spectrum of the effluent stream at two different dairy processing plants (a Drier Plant and Cheese Factory). The spectra exhibited significant variability. As an alternative to the partial least squares regression methods usually used in the online UV/Vis field a non-negative matrix factorisation technique was employed to compress the spectral data.