Publications by authors named "R D Crowley"

Article Synopsis
  • The study aimed to evaluate the most reliable evidence for managing X-linked hypophosphatemia (XLH) in adults to help shape treatment recommendations.
  • After reviewing over 4,000 records, only one clinical trial and two observational studies met the criteria, showing that burosumab likely helps with pain from fractures but has a limited effect on other symptoms like fatigue and stiffness.
  • There are currently no strong comparisons between burosumab and conventional treatments, highlighting a significant gap in data regarding their long-term effectiveness on important patient outcomes.
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Background: Complete clot ingestion (CCI) is defined as full ingestion of the clot into the catheter or pump canister without any external clot remnants at the catheter tip. The aim of this study was to demonstrate that using the CCI metric in vitro, partially ingested ('corked') clots pose a higher risk of distal emboli given distal emboli may exist in the setting of Thrombolysis In Cerebral Infarction 3 (TICI 3) revascularization.

Methods: Thrombectomies using an in vitro synthetic clot analog were conducted across six catheters using the novel ALGO Smart Pump with Adaptive Pulsatile Aspiration (APA) (Von Vascular Inc, Sunrise, FL) and compared against the Penumbra static Engine Pump (Alameda, CA).

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Underwater noise data were collected from 84 pile drives during bridge construction at various sites in Florida. These data were used to develop an empirically based model for underwater transmission loss associated with root mean squared, peak, and sound exposure level values. The model was verified using readings from other datasets as well as data from this study, and it appeared to reproduce reported transmission loss coefficient values well when data were curated to match data used in the empirical model's development and limited to situations where robust data were used in model development.

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Endometriosis is a complex condition that is often underdiagnosed, leaving rare but serious risks such as malignant transformation overlooked in many cases. Malignant transformation, especially in extra-gynaecological sites, poses significant diagnostic and therapeutic challenges. We present a case of an endometriosis-associated intestinal tumour diagnosed in a patient with exposure to oestrogen-only hormone replacement therapy (HRT) on a background of total abdominal hysterectomy and bilateral oophorectomy performed three decades before her presentation.

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Background: Subacute and chronic subdural hematomas are common and frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk of reoperation remains unclear.

Methods: In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or chronic subdural hematoma with an indication for surgical evacuation to undergo middle meningeal artery embolization plus surgery (treatment group) or surgery alone (control group).

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