Publications by authors named "R Croner"
Article Synopsis
- * Among 3754 patients analyzed, results showed that males lost an average of 19.3 kg and females 16.3 kg after six months, with females experiencing greater effective weight loss relative to men.
- * GBI appears to be a valuable treatment option for mildly obese patients and can also serve as a preparatory step for later bariatric surgery, with some advantages in health outcomes, particularly for women regarding hypertension remission.
Diagnostics (Basel)
October 2024
Article Synopsis
- A retrospective study assessed the diagnostic effectiveness of C-reactive protein (CRP) and leucocyte count in differentiating complicated (CAA) from uncomplicated acute appendicitis (UAA) based on EAES guidelines, involving 285 patients in Germany from 2019 to 2021.
- The study found that CRP levels were significantly higher in CAA patients compared to UAA patients, showing medium diagnostic value for identifying CAA and a cutoff at 44.3 mg/L, while leucocyte count had a low predictive value.
- Higher CRP levels were linked to an increased risk of postoperative complications and longer hospital stays, indicating that CRP is a useful marker for diagnosing CAA within the EA
Front Pharmacol
September 2024
Article Synopsis
- Glioblastoma (GBM) is a highly aggressive brain tumor, with a subtype called mesenchymal (MES-GBM) known for its resistance to treatment.
- Trihexyphenidyl (THP), an existing medication, has been shown to effectively inhibit the growth and survival of MES-GBM cells while sparing non-tumor cells.
- The study suggests THP's potential for repurposing as a cancer treatment, but more research is needed to clarify its mechanisms of action and establish optimal treatment protocols.
Surg Endosc
December 2024
Article Synopsis
- The study investigates how the length of time taken during liver surgeries affects the likelihood of postoperative complications in patients undergoing different types of liver resections.
- A total of 5,424 patients were analyzed from multiple centers between 2000 and 2022, focusing on procedures like right hemihepatectomy, technically major resection, and left lateral sectionectomy.
- Results show that patients in the longest operative time group had a significantly higher risk of complications, particularly in various surgical approaches like open, laparoscopic, and robotic surgeries.
Article Synopsis
- A study was conducted to compare robotic minor liver resections (RMLR) with laparoscopic minor liver resections (LMLR) in patients undergoing surgery on the anterolateral liver segments.
- The analysis included over 10,000 patients and employed propensity score matching to balance the groups for accuracy in comparisons.
- Results indicated RMLR had benefits like less blood loss, lower major morbidity, and shorter hospital stays than LMLR, although the difference in 30-day readmission rates suggested RMLR may have some drawbacks.
