Publications by authors named "R Crapnell"
The use of 3D-printed electrodes is reported fabricated from in-house conductive filament composed of a mixture of recycled poly (lactic acid) (rPLA), graphite (Gpt), and carbon black (CB) for fast detection of the abused drug ketamine. Firstly, the performance of these electrodes was evaluated in comparison to 3D-printed electrodes produced employing a commercially available conductive filament. After a simple pretreatment step (mechanical polishing), the new 3D-printed electrodes presented better performance than the electrodes produced from commercial filament in relation to peak-to-peak separation of the redox probe [Fe(CN)]/ (130 mV and 759 mV, respectively), charge transfer resistance (R = 1.
View Article and Find Full Text PDFLaser-induced graphene, which was first reported in 2014, involves the creation of graphene by using a laser to modify a polyimide surface. Since then, laser-induced graphene has been extensively studied for application in different scientific fields. One beneficial approach is the use of laser-induced graphene coupled with electrochemistry, where there is a growing need for disposable, conductive, reproducible, flexible, biocompatible, sustainable, and economical electrodes.
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- The review focuses on the electroanalytical methods for determining levels of mycophenolate mofetil and mycophenolic acid, both important in immunosuppression for organ transplant patients and autoimmune disorders.
- While laboratory techniques are common for measuring these substances, there is potential for developing more accessible, field-based measurement methods.
- The authors highlight the advantages of electroanalysis, including its selectivity, sensitivity, cost-effectiveness, and capacity for on-site use, while suggesting avenues for future research in this area.
Article Synopsis
- Additive manufacturing electrochemistry has mainly been limited to aqueous environments, but the introduction of a new conductive poly(propylene) filament can broaden its applications to organic electrochemistry and electrosynthesis.
- The filament, containing 40 wt% carbon black, demonstrates impressive thermal stability, flexibility at low temperatures, and high conductivity, allowing for the creation of reliable additive-manufactured electrodes.
- These electrodes excel in multiple electrochemical applications, including highly sensitive environmental sensing, stability in organic solvents over time, and efficient electrosynthesis of chlorpromazine, showing potential to significantly advance the field.
Norovirus (NoV) is the predominant cause of foodborne illness globally; current detection methods are typically expensive, have inadequate sensitivities, and utilize biological receptors with poor stability. Therefore, accurate, cost-effective, and highly stable detection methods are needed to screen for NoV in foods. We developed molecularly imprinted polymer nanoparticles (nanoMIPs) to detect NoV using a small target epitope (12 amino acids) with a solid-phase synthesis approach.
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