Publications by authors named "R Coupeau"
Bone remodeling is energetically demanding process. Energy coming from nutrients present in the diet contributes to function of different cell type including osteoblasts, osteocytes and osteoclasts in bone marrow participating in bone homeostasis. With aging, obesity and osteoporosis the function of key building blocks, bone marrow stromal cells (BMSCs), changes towards higher accumulation of bone marrow adipose tissue (BMAT) and decreased bone mass, which is affected by diet and sex dimorphism.
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- Obesity can harm bones and fat handling in both mice and people.
- Omega-3 fatty acids may help improve how the body manages sugar and supports healthy bones in those with obesity.
- A study found that mice on a high-fat diet supplemented with omega-3s had better bone health and less fat in their bones compared to those only on the high-fat diet.