Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men.

Purpose: Finasteride, an oral type 2, 5alpha-reductase inhibitor, is used in 1 mg. daily doses for the treatment of male pattern hair loss. A dose of 5 mg.

Continuation of a donor oocyte pregnancy in a functionally agonadal patient without early oestrogen support.

A 40 year old functionally agonadal patient was the recipient of fertilized donated oocytes. She accidentally discontinued all oestrogen support on the day preceding embryo transfer until it was reinstated 12 days later. However, a pregnancy was established and resulted in the birth of healthy normal twin infants.

Treatment options for infertile couples.

Fast-developing technologies in infertility treatment make it a prime subject for review. In this paper, we revisit some of the basic biology of the male and female reproductive systems and point out where these systems break down. We then discuss some of the many technical treatment options available for the infertile couple and indicate where and when these technologies are best applied.

A novel ovarian stimulation protocol for use with the assisted reproductive technologies.

Objective: To determine whether a new ovarian stimulation protocol termed "minimal stimulation" provides pregnancy rates (PRs) comparable with those in a conventional full stimulation protocol for patients undergoing assisted reproductive technologies (ART).

Design: Prospective, nonrandomized study of patients in minimal stimulation or full stimulation, followed by standard IVF and zygote intrafallopian transfer or uterine-ET.

Setting: The ART program of the Mayo Clinic, Rochester, Minnesota.

A successful assisted reproductive technology satellite program.

A satellite program was implemented to provide IVF to interested infertile couples living in a five-state area. Thirty-six gynecologists were established as satellite sites after appropriate screening and training. No attempt was made to interchange reference serum specimens between laboratories.