Publications by authors named "R Cooksey"

Article Synopsis
  • The study explores factors influencing the start and stop of anti-IL-6 biologic DMARDs versus other bDMARDs in rheumatoid arthritis patients.
  • It analyzed data from a Welsh health database, focusing on treatment initiation and outcomes like infections and hospitalizations.
  • Findings show that anti-IL-6 bDMARDs were often chosen by patients with prior infections or kidney issues, and these patients had a lower treatment discontinuation rate compared to those on non-anti-IL-6 therapies.
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Background: Major burns are associated with multiple risk factors for thrombosis such as decreased mobilization and systemic inflammation. It is unclear if these factors are offset by the inherent lower thrombosis risk in the paediatric patient. As such there is no consensus on thromboprophylaxis for paediatric burns patients, in contrast to this being a mainstay of treatment in the adult population.

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Objectives: To examine the use of two coding systems used in the THIN UK primary care research database for the coding of telephone encounters between patient and healthcare professional in primary care. This is relevant to other research databases built on GP clinical systems. Consideration of telephone consultations was particularly important during the COVID-19 pandemic as remote interactions between patient and GP are more numerous than before and are likely to remain at a higher frequency.

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Ankylosing spondylitis is the second most common cause of inflammatory arthritis. However, a successful diagnosis can take a decade to confirm from symptom onset (via x-rays). The aim of this study was to use machine learning methods to develop a profile of the characteristics of people who are likely to be given a diagnosis of AS in future.

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