Publications by authors named "R Cloutier"
Objectives: US community pharmacies are a unique and underused health service setting for identifying and potentially intervening with patients at risk of opioid overdose or opioid use disorder with evidence-based practices such as screening, brief intervention, and referral to treatment (SBIRT). The aim of our study was to assess the feasibility of implementing SBIRT in community pharmacies in an urban county in terms of engagement, reach, and equity across the cascade of pharmacy screening and care.
Methods: Patients aged 18 years or older receiving a schedule II or III opioid prescription at 1 of 17 participating community pharmacies in Allegheny County, Pennsylvania, were invited to engage in SBIRT as part of Project Lifeline-II from June 2020 through January 2023.
The living coelacanth Latimeria (Sarcopterygii: Actinistia) is an iconic, so-called 'living fossil' within one of the most apparently morphologically conservative vertebrate groups. We describe a new, 3-D preserved coelacanth from the Late Devonian Gogo Formation in Western Australia. We assemble a comprehensive analysis of the group to assess the phylogeny, evolutionary rates, and morphological disparity of all coelacanths.
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- - The study analyzes plasma samples from 318 COVID-19 patients to understand how RNAemia, delayed antibody responses, and inflammation affect patient outcomes, revealing four distinct patient clusters based on severity and survival probability.
- - Critically ill patients were categorized into good prognosis and high-fatality clusters, while non-critical survivors were divided into high and low early antibody responders, each showing different patterns in antibody development and inflammation.
- - The findings indicate that high-fatality patients have specific genomic signatures linked to severe COVID-19, and both critical and non-critical patients with delayed antibody responses exhibit persistent interferon (IFN) activity, suggesting that high IFN levels might hinder the body's ability to build effective immunity.
This paper explores the design and experimental validation of a three-degree-of-freedom variable inertia generator. An inertia generator is a handheld haptic device that renders a prescribed inertia. In the mechanism proposed in this paper, three-dimensional torque feedback is achieved by accelerating three pairs of flywheels mounted on orthogonal axes.
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- The study focused on the implementation of SBIRT (screening, brief intervention, and referral to treatment) in Pennsylvania to identify unhealthy substance use and assist in treatment.
- Researchers analyzed data from 1,364 patients screened at seven primary care sites and found significant changes in risk categories between the two screenings.
- Results showed that 44% of patients had a decreased risk while 56% had an increased risk, highlighting the need for more frequent screening to effectively monitor substance use and improve patient care.