Leukotoxin A Production and Release by JP2 and Non-JP2 Genotype in Relation to Culture Conditions.

Aggressive forms of periodontitis, especially in young patients, are often associated with an increased proportion of the Gram-negative bacterium of the microbiota of the affected periodontal sites. One of the virulence factors of is a leukotoxin (LtxA) that induces a pro-inflammatory cell death process in leukocytes. exhibits a large genetic diversity and different genotypes vary in LtxA production capacity.

Association of and its RTX toxin gene with periodontal attachment loss, and in synergy with .

The Gram-positive bacterium, is an oral pathogen, and approximately 50% of known strains encode a recently identified repeat-in-toxin (RTX) protein, FtxA. By assessing a longitudinal Ghanaian study population of adolescents (10-19 years of age; mean age 13.2 years), we recently discovered a possible correlation between deep periodontal pockets measured at the two-year follow-up, presence of the gene, and a high quantity of .

Age-Related Subgingival Colonization of , and -A Pragmatic Microbiological Retrospective Report.

The aim of this study was to compare data about the prevalence and proportions of the bacterial species , , and in periodontitis pocket samples collected from young, <35 years, and old, >35-year-old patients, YP and OP, respectively. The results from the analyses of a total of 3447 subgingival plaque samples analyzed for clinical diagnosis purposes by cultivation regarding the proportions of these species were collected from a database and elucidated. The prevalence of A.

and as Associated with Periodontal Attachment Loss in a Cohort of Ghanaian Adolescents.

The aims of the present study were to document the presence of and the emerging oral pathogen , as well as to identify genotypes of these bacterial species with enhanced virulence. In addition, these data were analyzed in relation to periodontal pocket depth (PPD) and the progression of PPD from the sampled periodontal sites during a two-year period. Subgingival plaque samples were collected from 172 periodontal pockets of 68 Ghanaian adolescents.

Radiographic and clinical signs of periodontitis and associated bacterial species in a Swedish adolescent population.

Background: Periodontitis in adolescents has historically been rare in the Nordic countries but could be expected to increase due to changing demographics. The primary aim was to cross-sectionally examine the presence of radiographic bone loss in adolescents in Västerbotten County, Sweden. The secondary aim was to compare periodontal and microbial parameters, as well as demographic patterns, between controls without bone loss and cases with bone loss.