Symptoms, Quality of Life, and Executive Function in Children Who Snore.

Introduction: Mild sleep-disordered breathing (mSDB) in children is associated with both neurobehavioral morbidity and reduced quality of life (QOL). However, the association between symptom burden and QOL with executive function is not well understood, and it is not known whether QOL and symptom burden may help identify children with neurocognitive dysfunction.

Objective: To assess associations among executive function, QOL, and symptom burden in children with mSDB.

Changes in sleep-disordered breathing severity and post-stroke outcomes in the first year after stroke.

Background: Sleep-disordered breathing (SDB) is common among stroke survivors and is associated with worse functional, cognitive, and neurologic outcomes after stroke. Little is known about the association between changes in SDB and changes in these outcomes over time.

Methods: Ischemic stroke (IS) patients identified through the Brain Attack Surveillance in Corpus Christi project were offered SDB testing with a portable respiratory monitor (ApneaLink Plus) shortly after stroke, and at 3-, 6-, and 12-months post-stroke.

Sex-specific dementia risk in known or suspected obstructive sleep apnea: a 10-year longitudinal population-based study.

Study Objectives: To evaluate sex-specific associations between known or suspected obstructive sleep apnea (OSA) and dementia risk over 10 years among older women and men.

Methods: This study included 18 815 women and men age 50+ years (dementia-free at baseline) who participated in the Health and Retirement Study (HRS), a nationally representative cohort of US adults. Presence of OSA was defined by self-reported diagnosis or key HRS items that correspond to elements of a validated OSA screening tool (STOP-Bang).

Comparative effectiveness of cognitive behavioural therapy, modafinil, and their combination for treating fatigue in multiple sclerosis (COMBO-MS): a randomised, statistician-blinded, parallel-arm trial.

Background: Fatigue is one of the most disabling symptoms reported by people with multiple sclerosis. Although behavioural and pharmacological interventions might be partly beneficial, their combined effects have not been evaluated for multiple sclerosis fatigue, or examined with sufficient consideration of characteristics that might affect treatment response. In this comparative effectiveness research trial, we compared the effectiveness of cognitive behavioural therapy (CBT), modafinil, and their combination for treating multiple sclerosis fatigue.