Publications by authors named "R Chaulagain"
Background: UC patients suffer more from colorectal cancer (CRC) than the general population, which increases with disease duration. Early colonoscopy is difficult because ulcerative colitis-associated colorectal cancer (UCAC) lesions are flat and multifocal. Our study aimed to identify promising UCAC biomarkers that are complementary endoscopy strategies in the early stages.
View Article and Find Full Text PDFIntroduction: The nutritional status of elderly people is crucial for healthy aging, enabling them to maintain productive lives and reduce the progression of chronic diseases. Given that the quality of life tends to decline with age, it becomes particularly crucial for elderly individuals. Therefore, this study was aimed to find out the prevalence of elderly patients at risk of malnutrition in a tertiary hospital.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the recurrence and malignant transformation (MT) risks associated with oral leukoplakia (OL), finding a 22% recurrence rate after surgical excision.
- Laser-based surgical techniques, particularly the combination of laser excision and vaporization, are identified as the most effective in reducing OL recurrence compared to other methods.
- Factors such as advanced age, female sex, inadequate surgical margins, and specific behaviors like betel quid chewing increase the likelihood of recurrence and MT in OL patients.
Background: Hepatocellular carcinoma (HCC), theseventh most common cancer worldwide, is characterized by a high mortality rate, advanced diagnosis, and susceptibility to extrahepatic metastasis. Numerous studies have shown that DNA methylation is a crucial factor in epigenetic modifications and regulation of carcinogenesis.
Methods: HCC patient data were sourced from the TCGA dataset as a training set, while GSE116174 was used as an external validation set for verification.
Antifungal susceptibility pattern of species isolated from pregnant women.
Front Cell Infect Microbiol
August 2024
Article Synopsis
- The study focuses on the prevalence and antifungal resistance of opportunistic yeast infections, specifically among pregnant women in Hajjah governorate, Yemen, finding a high prevalence rate of 61.4%.
- Most cases were linked to certain factors, like age (71.9% in women aged 24-30), education level, trimester, and pregnancy history.
- Significant resistance to common antifungal medications, including clotrimazole and itraconazole, was observed, highlighting the need for health education on vaginitis and tailored antifungal treatments.