Synergistic effect of mulch and nitrogen management on growth and essential oil yield of Salvia sclarea L.

Balanced plant nutrition and optimal micro-climate are critical for achieving higher production sustainably. Substituting mineral fertilizers with organic amendments under water-conserving strategies like mulch can enhance the quality and yield and improve soil health. Therefore, a two-year study was conducted to examine the synergistic effects of mulch and reducing inorganic fertilizers and partially substituting organic amendments on essential oil (EO) yield and its composition, and soil properties in Salvia sclarea, an industrially important crop.

Copper induced augmentation of antibiotic resistance in Acinetobacter baumannii MCC 3114.

Increasing antibiotic resistance among the common nosocomial pathogen i.e. Acinetobacter baumannii poses life threat to the health care workers as well as to the society.

Autologous simple limbal stem cell transplantation with conjunctival autograft in chronic unilateral total LSCD with severe symblepharon due to severe alkali burn.

This report details the case of a middle-aged man with chronic unilateral total limbal stem cell deficiency with severe symblepharon in his left eye with upper lid mechanical ptosis, restricted ocular movements and visual acuity limited to counting fingers at 2 feet. 9 months prior to his first visit, he sustained an accidental unilateral alkali injury to the left eye. He underwent autologous simple limbal epithelial transplantation combined with conjunctival autograft in the left eye.

Phosphoproteomics guides low dose drug combination of cisplatin and silmitasertib against concurrent chemoradiation resistant cervical cancer.

Cisplatin-based concurrent chemoradiotherapy (CCRT) is the standard treatment for cervical patients with locally advanced disease. Despite the improved survival rates and prognosis observed in patients undergoing CCRT, over 30-40% do not achieve complete response and are at risk of locoregional recurrence. Targeting crucial molecules that confer resistance may improve the clinical outcomes of the treatment resistant patient cohort.

Computational dissection through network pharmacology and structure-based analysis unravels mechanistic actions of bioactive compounds in a hepatoprotective herb, for the treatment of NAFLD and NASH.

Non-Alcoholic fatty liver disease has become a silent pandemic worldwide with no authorized medicine available. is a traditional hepatoprotective herb wherein extracts provide therapeutic efficacy but not the individual compounds. Hence, the aim of the study is exploration of active molecules in extracts and identification of mechanistic actions to pinpoint potential leads towards drug development.