Publications by authors named "R Cerna"

Article Synopsis
  • Recent research indicates that DCLK1 is overexpressed in various cancers, serving as a marker for cancer stem cells and linking to tumor immune responses.
  • The study investigates DCLK1 expression in hepatocellular carcinoma (HCC) using a modified model and several web-based tools to analyze its correlation with cancer stage and clinicopathological factors.
  • The findings suggest that DCLK1 is significantly involved in HCC progression and correlates with immune cell infiltration, presenting it as a potential prognostic biomarker for cancer outcomes.
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Introduction And Hypothesis: Educational interventions have been effective in improving postpartum knowledge, performance of pelvic floor exercises, and bowel-specific quality-of-life. Our primary objective was to determine if a video-based educational intervention on pelvic floor disorders (PFDs) would increase Spanish-speaking women's knowledge of PFDs, and secondarily to assess if it would decrease pelvic floor symptoms. We hypothesized that Spanish-speaking women would improve their pelvic floor knowledge and symptoms post-intervention.

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Article Synopsis
  • Fully grown mammalian oocytes rely on RNA transcripts made earlier in development for their functions, regulated by RNA localization and translation mechanisms.
  • In mouse oocytes, three cap-dependent translational repressors (4E-BP1, 4E-BP2, and 4E-BP3) are produced at the mRNA level, but only 4E-BP1 is active as a protein, promoting translation after nuclear envelope breakdown through phosphorylation.
  • Key regulators of 4E-BP1 phosphorylation during meiosis are mTOR and CDK1 kinases, with evidence suggesting that this regulatory pathway is also present and likely functions similarly in human oocytes.
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The fully grown mammalian oocyte is transcriptionally quiescent and utilizes only transcripts synthesized and stored during early development. However, we find that an abundant RNA population is retained in the oocyte nucleus and contains specific mRNAs important for meiotic progression. Here we show that during the first meiotic division, shortly after nuclear envelope breakdown, translational hotspots develop in the chromosomal area and in a region that was previously surrounded the nucleus.

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Non-linear interactions in coherent gases are not only at the origin of bright and dark solitons and superfluids; they also give rise to phenomena such as multistability, which hold great promise for the development of advanced photonic and spintronic devices. In particular, spinor multistability in strongly coupled semiconductor microcavities shows that the spin of hundreds of exciton-polaritons can be coherently controlled, opening the route to spin-optronic devices such as ultrafast spin memories, gates or even neuronal communication schemes. Here we demonstrate that switching between the stable spin states of a driven polariton gas can be controlled by ultrafast optical pulses.

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