Publications by authors named "R Catalano"
Article Synopsis
- Filamin A (FLNA) is found at lower levels in adrenocortical carcinomas (ACC) compared to adenomas (ACA), and its presence is linked to less aggressive tumor behavior due to its role in regulating IGF1R signaling.
- The study investigated the expression of Wee1 kinase in ACC and how it is influenced by FLNA, revealing increased Wee1 and decreased FLNA proteins in ACC, along with insights into the effects of the Wee1 inhibitor AZD1775.
- Findings indicate that FLNA promotes the degradation of Wee1, and that low FLNA levels in ACC lead to heightened Wee1, suggesting that targeting Wee1 with inhibitors could be a promising treatment strategy for FLNA-deficient
Breast cancer is the most prevalent cancer among women globally, making early and accurate detection essential for effective treatment and improved survival rates. This paper presents a method designed to detect and localize breast cancer using deep learning, specifically convolutional neural networks. The approach classifies histological images of breast tissue as either tumor-positive or tumor-negative.
View Article and Find Full Text PDFThis paper presents a comprehensive study of hydrogenated amorphous silicon (a-Si)-based detectors, utilizing electrical characterization, Raman spectroscopy, photoemission, and inverse photoemission techniques. The unique properties of a-Si have sparked interest in its application for radiation detection in both physics and medicine. Although amorphous silicon (a-Si) is inherently a highly defective material, hydrogenation significantly reduces defect density, enabling its use in radiation detector devices.
View Article and Find Full Text PDFPregnancies ending before 26 weeks contribute 1% of births but 40% of infant deaths in the United States. The rate of these "periviable" births to non-Hispanic (NH) Black women exceeds four times that for NH whites. Small male periviable infants remain most likely to die.
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