Background: Invasive fungal infections can cause serious complications after lung transplant; therefore, prophylaxis with posaconazole is common. The posaconazole delayed-release (DR) tablet is preferred. Although the package insert states DR tablets cannot be crushed, recent data suggest it is reasonable.
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September 2024
Currently, the number of vehicles in circulation continues to increase steadily, leading to a parallel increase in vehicular accidents. Among the many causes of these accidents, human factors such as driver drowsiness play a fundamental role. In this context, one solution to address the challenge of drowsiness detection is to anticipate drowsiness by alerting drivers in a timely and effective manner.
View Article and Find Full Text PDFFreezing of gait, characterized by involuntary interruptions of walking, is a debilitating motor symptom of Parkinson's disease that restricts people's autonomy. Previous brain imaging studies investigating the mechanisms underlying freezing were restricted to scan people in supine positions and yielded conflicting theories regarding the role of the supplementary motor area and other cortical regions. We used functional near-infrared spectroscopy to investigate cortical haemodynamics related to freezing in freely moving people.
View Article and Find Full Text PDFNotable efforts have been devoted to the development of biomechanical models of the spine, so the development of a motion system to control the spine becomes expressively relevant. This paper presents a fuzzy controller to manipulate the movement of a 3D robotic mechanism of the lumbar spine, which is driven by tendons. The controller was implemented in Matlab/Simulink R2023a software, MathWorks (Brazil), considering mathematical modeling based on the Lagrangian methodology for simulating the behavior of the lumbar spine dynamic movement.
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