Agriculture data sharing review.

This study conducts a bibliometric analysis of 252 scientific publications from 2001 to 2023, exploring the evolution and emerging trends in agricultural data spaces. Analyzing articles from the Web of Science and Scopus databases, we address six research questions: the current and interconnected key topics in agricultural data spaces (RQ1), the evolution of research themes over time (RQ2), emerging trends in the field (RQ3), the identification of leading researchers (RQ4), and the primary funding sources for this research area (RQ5), the relationship among research data and small farmers (RQ6). Our findings reveal a shift from traditional to innovative research themes, such as the increasing focus on the Internet of Things (IoT), Blockchain, and Digital Storage.

Later lines of systemic therapy in patients with metastatic colorectal cancer: real-world data from a setting with barriers to access cancer therapies.

Background: Regorafenib and trifluridine/tipiracil (TFD/TPI) are oral systemic therapies with survival benefit in chemorefractory metastatic colorectal cancer (mCRC) patients, but they are not widely available worldwide. We aimed to evaluate the treatment patterns and outcomes of patients with limited access to these drugs.

Methods: Retrospective study involving 510 patients with mCRC who were treated at five different centers in Brazil, from January 2011 to December 2019.