[Celiac disease (familial) associated with sarcoidosis. Clinical case and review of the literature].

The authors report a case of a 42 year-old patient, female, already suffering in 1990 from pulmonary sarcoidosis at 0 radiological stage, together with uveitis and relapsing erythema nodosum, with dyspepsia and weight loss which benefited from corticosteroidal therapy, repeatedly applied at the relapses of Erythema Nodosum. This therapy induced clinical recovery and marked weight gain. After 3 years (in 1993), the appearance of chronic diarrhoea, weight loss, oedemas of the lower limbs and altered laboratory findings which suggested malabsorbtive syndrome, made us verify with clinical-instrumental examinations (serum AGA IgA and IgG, Xilose test, perendoscopic jejunal biopsy) the diagnosis of fully clinically expressed adult coeliac disease.

[Thrombotic thrombocytopenic purpura (Moschowitz syndrome). A clinical case and review of the literature].

A case of young woman affected by relapsing Thrombotic Thrombocytopenic Purpura (TTP), probably beginning in September 1986 and relapsing after 6 years, in June 1992, is described. After a first Complete Remission due to Plasma Exchange and Antiplatelet Agents, the patient relapsed during maintenance therapy with Ticlopidine and, over 1 month, developed two relapses which were resistant to traditional therapy. Showing resistance even to Iloprost, the patient had a Complete Remission only after a 2nd IV bolus of Vincristine according to Gutterman's scheme (modified), with prolonged therapeutic wellbeing.

[Empty sella syndrome (ESS) associated with primary hyperparathyroidism. A clinical case and review of the literature].

The report describes a patient with coexisting primary hyperparathyroidism due to adenoma of the left superior lobe and the primary empty sella syndrome (ESS). Pathogenetic mechanisms, clinical pictures, associated illnesses and similarity between these diseases are discussed. A complete diagnostic procedure and follow-up is necessary even if the illnesses are oligosymptomatic.

[Primary non-Hodgkin's lymphoma of paranasal sinuses. Review of the literature and a case report].

A case of primary extranodal non-Hodgkin's lymphoma arising in paranasal sinuses, in an 89 year-old woman is reported. Histologically it was lymphoplasmacytoid, pleomorphic, diffuse, at intermediate grade of malignancy according to "Working formulation for clinical usage" in I EB stage. Complete resolution was obtained with polychemotherapy according to the scheme ProMACE-CytaBOM.

[Hashimoto's thyroiditis, idiopathic thrombocytopenic purpura (Werlhof's disease) and Steinert's dystrophia myotonica. A clinical case].

The authors report a rare association: Hashimoto's thyroiditis, thrombocytopenic idiopathic purpura (Werlhof's disease) and Steinert's myotonic dystrophia. The authors outline the fingerprints of each disease, report particular syndromes and compare that association to data of partially reviewed literature. They suppose a suggestive pathogenetic connection among these diseases, due to the coexistence of altered genetic, endocrine and autoimmune factors and consequently impaired cell membrane permeability.