Publications by authors named "R Calvino"
Acute myocardial infarction (AMI) is a pandemic in which conventional risk factors are inadequate to detect who is at risk early in the asymptomatic stage. Although gene variants in genes related to cholesterol, which may increase the risk of AMI, have been identified, no studies have systematically screened the genes involved in this pathway. In this study, we included 105 patients diagnosed with AMI with an elevation of the ST segment (STEMI) and treated with primary percutaneous coronary intervention (PPCI).
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to evaluate the impact of the PROGALIAM network on survival rates for ST-segment elevation myocardial infarction (STEMI) patients in northern Galicia from 2001 to 2013.
- - Researchers analyzed data from 6,783 STEMI patients, comparing outcomes before and after the implementation of PROGALIAM, finding that mortality rates were higher before its introduction and improved significantly afterwards.
- - Results indicated that PROGALIAM not only reduced overall mortality but also helped equalize survival outcomes across different regions, showing improved healthcare quality for STEMI patients in the area.
Type 1 diabetes (T1D) results from the destruction of pancreatic β-cells by the immune system, and CD8 T lymphocytes are critical actors in this autoimmune response. Pancreatic islets are surrounded by a mesh of nervous cells, the peri-insular Schwann cells, which are also targeted by autoreactive T lymphocytes and express specific antigens, such as the neurotrophic factor S100-β. Previous work has shown increased proliferative responses to whole S100-β in both human T1D patients and the nonobese diabetic (NOD) mouse model.
View Article and Find Full Text PDFArticle Synopsis
- Spontaneous self-terminating atrial fibrillation (AF) is a common heart rhythm issue, but the regulatory mechanisms are not well understood.
- A study analyzed the expression of microRNAs and transcription factors in pig heart samples during AF, revealing a significant reduction in factors like Pitx2, Tbx5, and Myocd with corresponding increases in specific miRNAs.
- The findings suggest that changes in miRNA levels and transcription factor expression play a crucial role in triggering AF, making them important for understanding the condition.
Comparison of paclitaxel and everolimus-eluting stents in ST-segment elevation myocardial infarction and influence of thrombectomy on outcomes. ESTROFA-IM study.
Rev Esp Cardiol (Engl Ed)
December 2014
Introduction And Objectives: We sought to compare the long-term clinical outcome of with ST-segment elevation myocardial infarction treated with paclitaxel-eluting stents or everolimus-eluting stents and the influence of thrombectomy on outcomes.
Methods: The ESTROFA-IM is a multicenter retrospective registry collecting consecutive patients with infarction treated with these stents in 16 centers. Propensity-score matching was performed to select comparable stent groups and comparable groups with and without thrombectomy.