Exploring Neurobehaviour in Zebrafish Embryos as a Screening Model for Addictiveness of Substances.

Tobacco use is the leading cause of preventable death worldwide and is highly addictive. Nicotine is the main addictive compound in tobacco, but less is known about other components and additives that may contribute to tobacco addiction. The zebrafish embryo (ZFE) has been shown to be a good model to study the toxic effects of chemicals on the neurological system and thus may be a promising model to study behavioral markers of nicotine effects, which may be predictive for addictiveness.

A survey of client experiences with orthotics using the QUEST 2.0.

Introduction: Hand orthoses are designed to relieve pain, immobilize a body part and protect the injury site, prevent or correct deformity, and promote healing in the body. Practitioners who prescribe and create orthoses are reliant on patient adherence to achieve desired outcomes in treatment. Understanding client preferences may promote better orthotic intervention outcomes.