Rationale & Objective: Recent evidence suggests people with nondialysis chronic kidney disease (ND-CKD) experience a substantial burden of symptoms, but informative large-scale studies have been scarce. We assessed the prevalence of symptoms and the association of overall symptom burden with quality of life in patients with moderate to severe CKD.
Study Design: Cross-sectional study.
Key Points: A large comprehensive analysis of patients undergoing KRT within Brazil's Public Health System from 2015 to 2023. We reported an increase in the age at which dialysis began and a decline in the adoption of peritoneal dialysis over the years. We showed better hemodialysis adequacy as measured by single-pool Kt/V.
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