Publications by authors named "R C Santa Barbara"
Article Synopsis
- - The study examines the clinical and histopathologic characteristics of eyelid cutaneous horns in five pediatric patients, with a focus on information from patient records and literature review.
- - Results showed that all lesions resolved either surgically or conservatively, with the average patient age being 6.6 years, and no signs of malignancy were found during histologic evaluations.
- - The findings suggest that pediatric eyelid cutaneous horns are linked to inflammatory conditions like hordeolum or chalazion and are generally benign, differing from adult cases that often involve neoplastic changes.
Purpose: To assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections alone and with a combination of anti-VEGF injections and photodynamic therapy (PDT).
Setting/venue: Department of Ophthalmology, University Hospital Southampton NHS Foundation Trust, United Kingdom.
Methods: Retrospective review of 95 Caucasian patients in a single centre with diagnosis of PCV between 2013 and 2018 were included.
Introduction: Keratoconus is a progressive disorder of the cornea that causes thinning (Sedaghat et al. in Sci Rep 11(1):11971, 2021), ectasia, and irregular astigmatism, resulting in poor visual acuity that cannot be corrected with standard sphero-cylindrical spectacle lenses. One feature distinguishing keratoconic corneas is ocular aberrations, manifesting up to five or six times the amount of higher-order aberrations than a normal, healthy eye.
View Article and Find Full Text PDFSerotonergic psychedelics are emerging therapeutics for psychiatric disorders, yet their underlying mechanisms of action in the brain remain largely elusive. Here, we developed a wide-field behavioral tracking system for larval zebrafish and investigated the effects of psilocybin, a psychedelic serotonin receptor agonist. Machine learning analyses of precise body kinematics identified latent behavioral states reflecting spontaneous exploration, visually-driven rapid swimming, and irregular swim patterns following stress exposure.
View Article and Find Full Text PDFBackground: To evaluate the long-term anatomical and functional outcomes of anti-Vascular Endothelial Growth Factor intravitreal injections (anti-VEGF IVI) in patients with type 3 macular neovascularisation (MNV) in real-world settings.
Methods: Retrospective review of patients with type 3 MNV who received anti-VEGF IVI between 2013 and 2020. Primary outcomes were best corrected visual acuity (BCVA) and central macular thickness (CMT).