Publications by authors named "R C Sa"
Autoimmune polyglandular syndrome type 3 (APS-3) is an uncommon condition marked by autoimmune thyroid disease (ATD) linked with other autoimmune issues, excluding Addison's disease. We report a case of a 41-year-old man who was hospitalized due to exhaustion and macrocytic anemia, later diagnosed with APS-3, which included Hashimoto's thyroiditis, pernicious anemia resulting from autoimmune gastritis, and pre-existing vitiligo. Diagnostic results indicated positive intrinsic factor antibodies, a gastric biopsy compatible with gastritis, elevated thyroid peroxidase antibodies, and significant findings from a thyroid ultrasound.
View Article and Find Full Text PDFBackground: Effective treatment of late antibody-mediated rejection (late AMR) is still an unmet medical need. Clearing donor-specific antibody (DSA) and preventing its rebound is the ideal goal of treatment.
Methods: We have summarized the clinical data from seven patients with late or chronic active AMR after renal transplantation who received daratumumab (Dara)-based treatment first (Phase 1) and then tocilizumab (TCZ) therapy (Phase 2).
Recent studies have discovered that wheat bran could stimulate digestive tract development, modulate intestinal microbiota, and improve the digestibility of fibrous ingredients in broilers. Wheat bran varies greatly in its chemical constituents. The objective of this study is to investigate how different types of wheat bran influence growth performance, nutrient digestion, and gut health in broiler chickens.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore how oxhorn cupping therapy (OHCT) impacts rheumatoid arthritis by analyzing proteins in the body fluid collected from patients after treatment.
- Thirty patients underwent OHCT, and researchers isolated and examined exosomes from the fluid to identify changes in protein expression, revealing 300 differentially expressed proteins (DEPs).
- Key pathways and genes associated with the treatment effects were identified, particularly related to signal transduction, with a notable shift in certain protein levels during and after treatment.
- Overall, the findings suggest that OHCT may have therapeutic effects on rheumatoid arthritis by altering exosomal proteins and pathways involved in the disease.
Introduction: Helicobacter pylori (H. pylori) is a major human pathogen whose increased antibiotic resistance poses a serious threat to human health.
Aim: The aim of this study is to further explore the association between H.