Publications by authors named "R C Nicole Rakotoarison"

Article Synopsis
  • * The study focused on 746 children aged 1-10, finding a 30% parasite infection rate, with certain parasites showing varying prevalence based on household socioeconomic factors like family income and maternal education.
  • * Results indicated that children from economically disadvantaged households and those with less educated mothers had higher infection rates, prompting the IRCOD project to work on educating mothers about hygiene and prevention strategies.
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Article Synopsis
  • Taenia solium infections, including taeniosis and cysticercosis, are prevalent yet underdiagnosed in rural Madagascar, particularly around Ranomafana National Park, prompting a study to evaluate their prevalence and risk factors.
  • A cross-sectional survey conducted in June 2016 revealed that 10 out of 459 participants had Taenia spp. eggs in their stool, predominantly the Asian genotype of T. solium, while seroprevalence of cysticercosis showed 27.5% to 29.8% of participants had specific antibodies.
  • Key risk factors identified included open defecation, large household sizes, and age over 15 years, while females and reliance on river
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Background: This study aimed to compare the prevalence of intestinal parasite infestations (IPIs) in stunted children, compared to control children, in Ankasina and Andranomanalina Isotry (two disadvantaged neighborhoods of Antananarivo, Madagascar), to characterize associated risk factors and to compare IPI detection by real-time PCR and standard microscopy techniques.

Methodology/principal Findings: Fecal samples were collected from a total of 410 children (171 stunted and 239 control) aged 2-5 years. A single stool sample per subject was examined by simple merthiolate-iodine-formaldehyde (MIF), Kato-Katz smear and real-time PCR techniques.

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Soil-transmitted helminth (STH) infections carry the highest number of disability adjusted life years among all neglected tropical diseases, disproportionately affecting low-income countries such as Madagascar.  This study describes the epidemiology of STH and S. stercoralis infections in twelve remote villages surrounding Ranomafana National Park (RNP), Ifanadiana, Madagascar.

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The interaction between Plasmodium vivax Duffy binding protein (PvDBP) and Duffy antigen receptor for chemokines (DARC) has been described as critical for the invasion of human reticulocytes, although increasing reports of P. vivax infections in Duffy-negative individuals questions its unique role. To investigate the genetic diversity of the two main protein ligands for reticulocyte invasion, PvDBP and P.

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