Publications by authors named "R C Najarian"
We report a patient who presented with a 4-month history of intermittent epigastric pain. Computed tomography (CT) angiography of the abdomen demonstrated a stenotic celiac trunk but also encasement of the common proper hepatic artery, gastroduodenal artery, and proper hepatic artery by an ill-defined hypoattenuating mass of the pancreatic head. Biopsy confirmed metastatic prostate cancer to the pancreas that occurred 4 years after radiation and androgen deprivation therapy.
View Article and Find Full Text PDFBackground: Valgus extension overload syndrome (VEOS) most commonly affects overhead athletes and consists of a constellation of conditions involving the medial, posterior, and lateral elbow, with the most widely discussed being ulnar collateral ligament (UCL) injuries. Many athletes with UCL tears also have findings consistent with other VEOS conditions, though these are not consistently symptomatic. Given the high rate of concomitant pathology, many authors have recommended performing arthroscopy at the time of UCL reconstruction (UCLR) to diagnose and address concomitant VEOS pathology; however, it is not known if this practice actually leads to a reduction in subsequent surgeries for VEOS conditions following index UCLR.
View Article and Find Full Text PDFArticle Synopsis
- Manual histological assessment for diagnosing NASH (Nonalcoholic Steatohepatitis) is inconsistent and not very responsive to changes in disease state, highlighting the need for better tools.
- A machine learning approach was developed to analyze liver histology more accurately by utilizing deep learning to evaluate features like steatosis and fibrosis, correlating well with expert opinions and predicting disease progression.
- The study introduces a new metric, the Deep Learning Treatment Assessment Liver Fibrosis score, which detects treatment effects missed by traditional methods, showcasing the potential of machine learning in improving NASH diagnosis and treatment monitoring.
Background: Microscopic ileitis and its association with pancolitis in adults with ulcerative colitis (UC) have been described. The incidence of ileitis and associations with colonic disease in pediatric UC have, however, not been thoroughly investigated. This study was undertaken to examine the prevalence of microscopic ileal inflammation at the time of initial diagnosis in a cohort of children with UC.
View Article and Find Full Text PDFBackground: The modified Jobe technique of ulnar collateral ligament (UCL) reconstruction has previously been biomechanically compared with primary repair augmented with internal bracing. However, the docking technique has not been compared with repair with internal bracing.
Hypothesis: Load to failure, gapping, and valgus opening angle are similar under valgus loading at 90° of flexion between repair with internal bracing and the docking technique for the UCL.