Publications by authors named "R C Mendel"
Objective: The goal of this study was to describe lacerations of the head and neck sustained among ice hockey players in the US.
Methods: Data on adult (20-65 years) ice hockey injuries were collected from the 2003-2022 National Electronic Injury Surveillance System (NEISS) database. Injuries of the head, neck, face, mouth, and ears were included, while those sustained as a spectator, coach, or on a non-ice surface were excluded.
Article Synopsis
- A significant portion of spontaneous intracerebral hemorrhages (ICH) arise from macrovascular causes, necessitating a swift diagnosis, often through invasive procedures like digital subtraction angiography (DSA), which aren't suitable for all patients.
- This study aimed to develop a new risk stratification score, the MACRO score, incorporating MRI findings to improve the identification of macrovascular causes of ICH.
- The MACRO score successfully incorporates various patient factors and MRI markers, demonstrating better predictive capabilities than current CT-based scores, validating its effectiveness in a diverse patient population.
Article Synopsis
- A significant portion of patients (1 in 10) experience epilepsy after having cerebral venous thrombosis (CVT), but it's challenging to predict who will be affected.* -
- Researchers created the DIAS3 prognostic score using clinical data from over 1,100 patients to assess the likelihood of developing post-CVT epilepsy based on six clinical variables.* -
- The study found a range of predicted risks for post-CVT epilepsy within one and three years, with successful validation of the score confirming its effectiveness in estimating individual risk.*
In all domains of life, the biosynthesis of the pterin-based Molybdenum cofactor (Moco) is crucial. Molybdenum (Mo) becomes biologically active by integrating into a unique pyranopterin scaffold, forming Moco. The final two steps of Moco biosynthesis are catalyzed by the two-domain enzyme Mo insertase, linked by gene fusion in higher organisms.
View Article and Find Full Text PDFMolybdenum (Mo) is an essential micronutrient across all kingdoms of life, where it functions as a key component of the active centers of molybdenum-dependent enzymes. For these enzymes to gain catalytic activity, Mo must be complexed with a pterin scaffold to form the molybdenum cofactor (Moco). The final step of Moco biosynthesis is catalyzed by the enzyme Mo-insertase.
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