Publications by authors named "R C J A van Vliet"

Article Synopsis
  • Previous research hinted at differences in cerebellar white matter integrity related to stages of Parkinson's disease (PD), but the progression of these changes over time was not well understood.
  • The study involved 124 patients with PD, who underwent multiple MRI scans to track microstructural integrity in cerebellar white matter, focusing on the connections between the cerebellum and other brain areas, while assessing clinical symptoms and dopamine levels.
  • Results showed a non-linear pattern in cerebellar white matter changes, highlighting an initial increase in integrity followed by a decline, which mirrored declines in dopamine levels and clinical symptoms, suggesting adaptive changes in the brain as PD progresses.
View Article and Find Full Text PDF
Article Synopsis
  • The study looks at the effects of high PEEP (positive end-expiratory pressure) versus low PEEP ventilation strategies on COVID-19 patients with acute respiratory distress syndrome during the second wave in the Netherlands.
  • A total of 790 patients were analyzed, showing that 22.5% of those on high PEEP died compared to 39.2% on low PEEP, indicating higher survival rates with high PEEP (HR 0.66).
  • The results suggest that using high PEEP ventilation could improve survival rates in ICU for patients suffering from COVID-ARDS.
View Article and Find Full Text PDF

Purpose: Our study aimed to assess the oncological outcomes of sentinel node dissection during radical prostatectomy according to nodal location in comparison to extended pelvic lymph node dissection.

Materials And Methods: Prospectively collected data of clinically node-negative patients who underwent prostatectomy and extended lymph node dissection with or without sentinel node from January 2013 to January 2023 were retrospectively analyzed. The primary end point was to assess oncological outcomes on the whole population.

View Article and Find Full Text PDF