Publications by authors named "R C Dorea"

Background: Staphylococcus aureus (S. aureus) is a pathogen responsible for a wide range of clinical manifestations and potentially fatal conditions. There is a paucity of information on the influence of androgens in the immune response to S.

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Article Synopsis
  • The COVID-19 pandemic has raised significant health concerns globally, making it essential to understand its clinical and epidemiological traits to inform control strategies.
  • A study in northeastern Brazil analyzed 115 severely ill COVID-19 patients in an ICU, revealing common symptoms such as dyspnea and cough, with many patients having multiple comorbidities, particularly hypertension.
  • Notably, having two or more comorbidities and lower platelet counts were associated with higher mortality, while cough emerged as a surprising protective factor against death.
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Qualitative antibody tests are an easy, point-of-care diagnostic method that is useful in diagnosing coronavirus disease 2019, especially in situations where reverse transcription-polymerase chain reaction is negative. However, some factors are able to affect its sensitivity and accuracy, which may contribute to these tests not being used as a first-line diagnostic tool.

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Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades. Cancer has a close relationship with the immune system and, although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity, studies have emphasized their roles in cancer pathogenesis. The Th17 immune response profile is involved in several types of cancer including urogenital, respiratory, gastrointestinal, and skin cancers.

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