Publications by authors named "R C CANTU"

 Cognitive impairment is a core feature of traumatic encephalopathy syndrome (TES), the putative clinical syndrome of chronic traumatic encephalopathy-a neuropathological disease associated with repetitive head impacts (RHI). Careful operationalization of cognitive impairment is essential to improving the diagnostic specificity and accuracy of TES criteria. We compared single- versus two-test criteria for cognitive impairment in their associations with CSF and imaging biomarkers in male former American football players.

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Background: Exertional heat stroke (EHS) is a leading cause of secondary school sport-related death; however, a longitudinal analysis on observed trends is lacking. Our purpose was to describe EHS deaths in United States secondary school athletes since the 1982/1983 academic year.

Hypothesis: EHS deaths will be primarily represented by football athletes and have a stable or increasing trend across a decade-by-decade analysis.

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Former American football players are at risk for developing traumatic encephalopathy syndrome (TES), the clinical disorder associated with neuropathologically diagnosed chronic traumatic encephalopathy (CTE). The objective of this study was to determine whether hyposmia is present in traumatic encephalopathy syndrome. The study included 119 former professional American football players, 60 former college football players, and 58 same-age asymptomatic unexposed men from the DIAGNOSE CTE Research Project.

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Importance: Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts (RHIs). Prior research suggests a dose-response association between American football play duration and CTE risk and severity, but this association has not been studied for ice hockey.

Objective: To investigate associations of duration of ice hockey play with CTE diagnosis and severity, functional status, and dementia.

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Article Synopsis
  • Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease linked to frequent head injuries, often seen in athletes and military personnel, with a focus on its relationship with aggression and family mental health history.
  • The study analyzed data from deceased male brain donors with CTE, aiming to determine if the presence of CTE affects the relationship between first-degree family history of mental illness (1°FHMI) and aggression, using structured assessments and various demographic controls.
  • Results indicated that 1°FHMI was significantly correlated with aggression scores in individuals with CTE, suggesting that CTE pathology may influence aggression differently than previously understood, while no such association was found in those without CTE.
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