Publications by authors named "R Bustos"
Assessment of Medication Adherence Using Mobile Applications in Chronic Obstructive Pulmonary Disease: A Scoping Review.
Int J Environ Res Public Health
September 2024
Chronic obstructive pulmonary disease (COPD) is a condition that significantly impacts both patients and healthcare systems. The management of COPD involves various pharmacological intervention strategies, and addressing the issue of low adherence to these strategies has become a subject of significant interest. In response to this concern, there has been a shift toward utilizing telemedicine and mobile applications.
View Article and Find Full Text PDFThe endocannabinoid system as a therapeutic target in neuropathic pain: a review.
Expert Opin Ther Targets
September 2024
Introduction: This review highlights the critical role of the endocannabinoid system (ECS) in regulating neuropathic pain and explores the therapeutic potential of cannabinoids. Understanding the mechanisms of the ECS, including its receptors, endogenous ligands, and enzymatic routes, can lead to innovative treatments for chronic pain, offering more effective therapies for neuropathic conditions. This review bridges the gap between preclinical studies and clinical applications by emphasizing ECS modulation for better pain management outcomes.
View Article and Find Full Text PDFMore than 70% of bacteria are resistant to all or nearly all known antimicrobials, creating the need for the development of new types of antimicrobials or the use of "last-line" antimicrobial therapies for the treatment of multi-resistant bacteria. These antibiotics include Glycopeptide (Vancomycin), Polymyxin (Colistin), Lipopeptide (Daptomycin), and Carbapenem (Meropenem). However, due to the toxicity of these types of molecules, it is necessary to develop new rapid methodologies to be used in Therapeutic Drug Monitoring (TDM).
View Article and Find Full Text PDFArticle Synopsis
- - Major Depressive Disorder (MDD) is a widespread mental health issue characterized by feelings of sadness, hopelessness, and a lack of interest in daily activities, and while there are several treatments available, they often don't work effectively.
- - A new treatment option, Auvelity®, combines dextromethorphan with bupropion and has recently been approved for adults with MDD, with this review analyzing its pharmacology, safety, and efficacy based on various studies.
- - The combination of these two drugs could serve multiple roles in treatment, including as a first-line option or for patients who haven't found relief with traditional therapies, showing potential for future applications in other disorders as well.
Article Synopsis
- Central obesity involves the growth of visceral fat, which increases metabolic risks, and recent drug studies, such as Liraglutide (LGT), aim to tackle this issue despite unclear mechanisms on how it impacts visceral fat.
- The study aimed to observe how LGT affects factors related to fat tissue remodeling and mitochondria in mice on a high-fat diet by categorizing them based on diet and drug administration.
- Results showed that LGT treatment led to smaller fat cells, increased blood vessel formation, improved fat tissue structure, and healthier mitochondria, indicating LGT's effectiveness in enhancing visceral fat behavior and functionality.