Long-term cryopreservation of dental stem cells.

Cryopreservation is a procedure of a long-term storage of cells and/or tissues at a temperature that prevents cell divisions and metabolic processes. Due to ability to self-renewal and differentiation into more specialised cells, stem cells may be helpful in repairing of other damaged organs or tissues. Cryopreservation allows the frozen genetic material to maintain its biological properties for a long time.

Selecting Collective Variables and Free-Energy Methods for Peptide Translocation across Membranes.

The selective permeability of cellular membranes is a crucial property for controlled transport into and out of cells. Molecules that can bypass the cellular machinery and spontaneously translocate across membranes could be used as therapeutics or drug carriers. Peptides are a prominent class of such molecules, which include natural and man-developed antimicrobial and cell-penetrating peptides.

Effect of artificial saliva on the mechanical properties of a polymer material reinforced with fiber, used in esthetic tooth restorations.

Background: The oral environment can negatively affect the physical properties of fiber-reinforced composite (FRC) materials, which can lead to the deterioration of mechanical stability and reduce the span of their clinical usefulness.

Objectives: The aim of this study was to determine the influence of artificial saliva on the selected mechanical properties of FRC.

Material And Methods: The core of the polymer material selected for the study was a bundle of ultrahighmolecular-weight polyethylene (UHMWPE) fibers.

Effect of Helical Kink on Peptide Translocation across Phospholipid Membranes.

Biological membranes present a major obstacle for the delivery of therapeutic agents into cells. Some peptides have been shown to translocate across the membrane spontaneously, and they could be thus used as drug-carriers. However, the advantageous peptide properties for the translocation remain unclear.

Laboratory and clinical evaluation of polymer materials reinforced by fibers used in dentistry.

Objective: Fiber-reinforced composites (FRC) because of high strength and a low mass can be widely applied in many fields of dentistry.

Materials And Methods: The types of fibers commonly used in dentistry with the description of physicochemical properties of the reinforcing phase and polymer resin, are specified. The influence of the method of fiber positioning in the sample, their diameter, length and shape of fibers visible in cross-section on the strength of the FRC material, are underlined.