Publications by authors named "R Bristow"
Objective: To evaluate the correlation in temporal trends in obesity and endometrioid endometrial cancer incidence in the United States using two comprehensive national databases.
Methods: This is a cohort study in which data on endometrioid endometrial cancer were obtained from the U.S.
This article addresses the role of surgery in the management of gynecologic cancers with liver metastases. The authors review the short-term and long-term outcomes of aggressive resection through retrospective and randomized studies. Although the data supporting aggressive resection of liver metastasis are largely retrospective and case based, the randomized control data to address neoadjuvant versus chemotherapy have been widely criticized.
View Article and Find Full Text PDFBackground: Current treatment strategies for primary epithelial ovarian cancer (EOC) have significantly evolved, and the value of complete cytoreduction has not yet been reassessed. The study aimed to investigate the impact of residual disease after cytoreductive surgery for EOC on survival outcomes within the recent paradigm of frontline ovarian cancer treatment.
Methods: We searched relevant literature from the MEDLINE, Embase, and Cochrane Library databases to identify randomized controlled trials and prospective clinical trials of primary EOC published between 1 January 2000 and 22 September 2022.
Article Synopsis
- The study examined the national rate of emergency cesarean sections (ECS) in pregnant trauma patients (PTPs) who were involved in motor vehicle collisions (MVCs) and found that 8% underwent ECS.
- The median time from arrival to ECS was 115 minutes, with ECS patients showing higher rates of lung and spleen injuries, complications, and mortality compared to those who did not undergo ECS.
- Key risk factors for requiring ECS included severe head or abdominal injuries and an elevated shock index (SI), indicating the severity of injury.
Hypoxia-Associated Gene Signatures Are Not Prognostic in High-Risk Localized Prostate Cancers Undergoing Androgen Deprivation Therapy With Radiation Therapy.
Int J Radiat Oncol Biol Phys
October 2024
Purpose: Men with high-risk prostate cancer (PCa) are treated with androgen deprivation therapy (ADT) and radiation therapy, but the disease reoccurs in 30% of patients. Biochemical recurrence of PCa after treatment is influenced by tumor hypoxia. Tumors with high levels of hypoxia are aggressive, resistant to treatment, and have increased metastatic capacity.
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