Publications by authors named "R Brauer"

Unlabelled: In a population-based cohort study of menopausal women with common mental health diagnoses, SSRIs/SNRIs were associated with a 32% increased risk of osteoporotic fractures. The risk of osteoporotic fractures was particularly increased for longer periods of treatment with SSRIs/SNRIs (> 5 years) and in younger menopausal women (< 50 years old).

Purpose: To investigate the association between selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) and the risk of osteoporotic fractures (OF) in menopausal women with common mental health diagnoses (CMHD).

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Background: Opioid use for chronic noncancer pain (CNCP) is consistently higher in menopausal/postmenopausal women than in younger women or men, elevating their risk of opioid-related adverse health outcomes. Since pain severity increases with hormonal changes accompanying menopause, these women should be a focus of opioid stewardship efforts.

Aim: To examine opioid prescribing trends for CNCP in menopausal/postmenopausal women diagnosed with a musculoskeletal condition.

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Article Synopsis
  • Hormone replacement therapy (HRT) appears to have a safe cardiovascular profile for menopausal women, but there is limited data on its effects for those with diabetes.
  • A comprehensive review included 19 studies, of which most revealed a moderate risk of bias and indicated no significant increase in myocardial infarction (MI) risk among HRT users with diabetes.
  • Further investigation with better study designs is necessary to confirm these findings and better understand HRT’s impact on cardiovascular health in this demographic.
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Introduction: Antidepressants and menopause are risk factors which are independently associated with an increased risk of fractures. This review aims to investigate the risk of fragility fractures in women aged 40 and older and prescribed antidepressants.

Methods: A literature search was conducted using PubMed, Ovid Embase, Ovid PsychINFO, Web of Science, and Scopus from inception to 1 June 2024.

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