Publications by authors named "R Bragato"

Background: Cardiac involvement represents the main cause of death in patients with Fabry disease (FD). Echocardiography and cardiovascular magnetic resonance (CMR) have an established diagnostic role, but their prognostic value remains unresolved. This systematic review and meta-analysis sought to assess the prognostic implications of imaging parameters in FD.

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  • Mitral annular disjunction (MAD) is divided into pseudo-MAD (appears only during systole) and true-MAD (appears in both systole and diastole).
  • A study of 290 patients indicated that 50% had MAD, with 35% classified as true-MAD and 16% as pseudo-MAD.
  • The presence and extent of MAD were higher in patients with mitral valve prolapse (MVP), particularly in pseudo-MAD cases, and the inferior
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Background And Aims: The increasing use of assisted reproductive technology (ART) has raised concerns regarding its long-term cardiovascular safety due to potential hormonal imbalances and pro-thrombotic states. This study aimed to assess the long-term cardiovascular risk associated with fertility treatments in women.

Methods: Following PRISMA guidelines, a systematic review and meta-analysis was conducted in MEDLINE (via PubMed) from inception to January 2024.

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  • - This study investigated how mitral valve prolapse (MVP) affects heart structure, particularly focusing on the right side of the heart, in patients without significant regurgitation.
  • - Out of 49 MVP patients and 54 healthy controls, findings revealed that patients with MVP had enlarged tricuspid annuli and right atrial volumes compared to controls, even if they experienced tricuspid valve prolapse (TVP).
  • - The study concluded that changes in right heart structures in MVP patients should be carefully monitored, as increased tricuspid annular size was linked to higher TAPSE values, indicating a potential need for alternative measurements in assessing heart function.
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  • This study focused on how myocardial perfusion imaging (MPI) stress tests—specifically using stress cardiac magnetic resonance (sCMR) and single-photon emission computed tomography (SPECT-MPI)—affect the safety of high-risk patients undergoing non-cardiac surgery.
  • It involved 1,590 patients with heart disease or significant cardiovascular risk factors, finding that those who underwent stress tests had fewer cardiac complications within 30 days post-surgery (1.2% vs. 3.4%).
  • While both sCMR and SPECT-MPI reduced cardiac event rates equally, sCMR was shown to be more accurate for predicting the need for coronary artery revascularization.
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