Thiamphenicol in the treatment of extragenital gonorrhea.

One hundred ninety-two cases of gonorrhea, of which 23 were extragenital only or both genital and extragenital, were treated with a single oral dose of thiamphenicol (2.5 g in patients weighing less than or equal to 80 kg; 3 g in patients weighing greater than 80 kg). Of the 178 patients whose follow-up was possible, 176 patients (98.

Treatment of retroauricular keratinous cysts.

The excision method for the removal of keratinous cysts was modified and used for the treatment of such cysts in the retroauricular region. In 14 patients, 17 lesions were excised in this fashion with good to excellent results. The reasons for choosing this therapeutic modality and its modifications are discussed.

[Pharyngeal and anorectal gonorrhea. Incidence in Lausanne in 1981].

After a brief review of the literature on pharyngeal and anorectal gonorrhea, the authors report the incidence of this disease among 498 patients consulting for known or suspected venereal disease from January 1 to December 31 1981. 192 cases of gonorrhoea, of which 23 had extragenital localization, were treated with thiamphenicol (Urfamycine) in a single dose (2.5 g orally or 3 g in patients weighing over 80 kg).

In vitro responses of proliferating and non-proliferating cells to high doses of 17 beta-estradiol: cytochemical study.

The authors studied the effect of 17 beta-estradiol on the proliferation in vitro of chick embryo fibroblasts and human macrophages by microdensitometry, cytofluorometry, and autoradiography. For fibroblasts 17 beta-estradiol shortens the duration of the preparing period to mitosis, particularly of the synthetic phase (S) and has no effect on the duration of mitosis. For macrophages, which have temporarily lost their mitotic capacity, 17 beta-estradiol cannot induce mitotic division.