Predicting Unplanned Readmissions to the Intensive Care Unit in the Trauma Population.

Unplanned readmission to intensive care units (UR-ICU) in trauma is associated with increased hospital length of stay and significant morbidity and mortality. We identify independent predictors of UR-ICU and construct a nomogram to estimate readmission probability. We performed an IRB-approved retrospective case-control study at a Level I trauma center between January 2019 and December 2021.

Incidence of thrombotic complications related to weight-based dosing of activated prothrombin complex concentrate (aPCC) for reversal of apixaban and rivaroxaban in obese patients.

Factor eight inhibitor bypassing activity (aPCC) is recommended as a non-specific reversal agent for direct oral anticoagulants (DOACs) according to the 2017 American College of Cardiology (ACC) guidelines for reversal of anticoagulation. Factor eight inhibitor bypassing activity carries a black box warning for thrombotic events such as stroke, pulmonary embolism, deep vein thrombosis, and myocardial infarction, particularly at high doses. This was a retrospective, single-center, cohort investigation that included patients who received a weight-based dose of aPCC for reversal of apixaban and rivaroxaban between January 1, 2015, and December 31, 2020.

Erratum: Muons in Supernovae: Implications for the Axion-Muon Coupling [Phys. Rev. Lett. 125, 051104 (2020)].

This corrects the article DOI: 10.1103/PhysRevLett.125.

Administering DVT Prophylaxis Sooner Than 48 Hours Does Not Increase Failure of Nonoperative Management of High-Grade (Grades III-V) Splenic Injuries.

Splenic injuries are mostly treated with nonoperative management (NOM) with observation to monitor for continued hemorrhage and holding early chemical DVT prophylaxis to reduce the risk of NOM failure. Eberle et al demonstrated chemoprophylaxis prior to 72 hours didn't increase failure rate of NOM. We chose to extrapolate this finding and compare outcomes in high-grade splenic injuries (HGSI) with chemoprophylaxis before and after 48 hours.

Muons in Supernovae: Implications for the Axion-Muon Coupling.

The high temperature and electron degeneracy attained during a supernova allow for the formation of a large muon abundance within the core of the resulting protoneutron star. If new pseudoscalar degrees of freedom have large couplings to the muon, they can be produced by this muon abundance and contribute to the cooling of the star. By generating the largest collection of supernova simulations with muons to date, we show that observations of the cooling rate of SN 1987A place strong constraints on the coupling of axionlike particles to muons, limiting the coupling to g_{aμ}<10^{-8.