Publications by authors named "R Bolehovska"
Article Synopsis
- The study investigated how cervical load and bacterial DNA prevalence differ in pregnant women with preterm prelabor rupture of membranes (PPROM), particularly focusing on those with and without a history of cervical excisional treatment.
- Women who had cervical excisional treatment showed higher cervical loads of specific bacterial DNA compared to those without such a history.
- Additionally, the length of the excisional cone influenced the bacterial DNA levels, suggesting that longer cone lengths were associated with distinct microbiota changes.*
Article Synopsis
- The study aimed to identify expanded sequence types (eSTs) of Ureaplasma species from amniotic fluid in pregnancies affected by preterm prelabor rupture of membranes (PPROM) using a multilocus sequence typing scheme.
- It analyzed DNA samples from singleton pregnancies between 24 to 36 weeks gestation and discovered a total of 33 different eSTs, with 21 being novel, while the most common eST was found in 18% of the samples.
- The research categorized Ureaplasma DNA into two clusters, revealing that cluster II (U. urealyticum) had a higher rate of polymicrobial findings compared to cluster I (U. parvum), but there were
Changes in Relative Counts of Different Leukocyte Subpopulations in Peripheral and Umbilical Cord Blood of Women With Preterm Prelabor Rupture of Membranes With Respect to Intraamniotic Inflammation and Fetal Inflammatory Response Syndrome.
Am J Reprod Immunol
September 2024
Article Synopsis
- * Researchers analyzed blood samples from 52 pregnant women using flow cytometry to measure relative counts of various leukocyte subpopulations and defined IAI based on interleukin 6 levels in the amniotic fluid.
- * They found that while some differences in leukocyte counts were noted between mothers with IAI and FIRS, these changes weren't significant after considering the gestational age at the time of
Background: This study aimed to assess variations in the absolute counts of various leukocyte subsets in the peripheral blood of women with pregnancies affected by preterm prelabour rupture of membranes (PPROM), in relation to the presence of intra-amniotic inflammation (IAI).
Methods: The study included fifty-two women with singleton pregnancies experiencing PPROM. Absolute counts of different leukocyte subpopulations, such as granulocytes, monocytes, lymphocytes, T cells and their subsets, B cells and their subsets, and NK cells and their subsets, were measured in maternal peripheral blood samples using multicolour flow cytometry.
Objective: The aim of this study was to evaluate CD36 concentrations in amniotic fluid in pregnancies complicated by spontaneous delivery with intact fetal membranes (preterm labor, PTL) and preterm prelabor rupture of membranes (PPROM) with respect to the presence of the intra-amniotic infection.
Methods: A total of 80 women with PPROM and 71 with PTL were included in the study. Amniotic fluid samples were obtained by transabdominal amniocentesis.