Publications by authors named "R Bloch"

Mitochondrial dysfunction is a common feature of brain disorders. Mitochondria play a central role in oxidative phosphorylation; thus changes in energy metabolism in the brain have been reported in conditions such as Alzheimer's disease, Parkinson's disease, and stroke. In addition, mitochondria regulate cellular responses associated with neuronal damage such as the production of reactive oxygen species (ROS), opening of the mitochondrial permeability transition pore (mPTP), and apoptosis.

View Article and Find Full Text PDF

Background: Chronic limb-threatening ischemia (CLTI) is associated with high morbidity and mortality. As such, close follow-up is recommended to ensure patency of revascularization, limb viability, and optimization of cardiovascular risk factors. This study aimed to test the association between follow-up adherence and mortality, and to identify risk factors for nonadherence with recommended vascular follow-up.

View Article and Find Full Text PDF
Article Synopsis
  • - A case study outlines the treatment of a rare pancreaticoduodenal artery aneurysm (PDAA) in a 60-year-old woman with a unique anatomy—she had a hypoplastic celiac artery and blood supply coming from a dilated superior mesenteric artery.
  • - The patient underwent open surgical reconstruction, which involved resecting the PDAA and reconstructing the pancreaticoduodenal artery, leading to successful blood flow restoration during and after surgery.
  • - The surgical intervention was effective; the patient recovered well and was discharged five days post-op with normal liver function tests, indicating a promising management strategy for similar cases.
View Article and Find Full Text PDF
Article Synopsis
  • Harmful algal blooms (HABs) have become more common worldwide, posing health risks due to various toxins, and poison control data helps track these exposures.
  • This study analyzed 4,260 cyanoHAB exposure cases reported to U.S. poison control centers from 2010 to 2022, focusing on demographics, exposure circumstances, and health outcomes.
  • Findings showed most affected individuals were young children, with exposures primarily occurring in public areas, and the overall incidence of cyanoHAB cases increased significantly over the study period, although severe outcomes were rare.
View Article and Find Full Text PDF