Using platelet concentrates to treat maxillofacial tissue lesions.

Objectives: Platelet concentrates (PCs), which are blood products that are abundant in platelets and growth factors, have become pivotal in treating maxillofacial tissue lesions due to their capacity for promoting bone and soft tissue recovery. This review will provide some recent progress of the use of platelet concentrates to treat lesions on maxillofacial tissues.

Subjects: We reviewed the mechanisms by which PCs promote wound healing and tissue recovery and summarized the application of PCs in the treatment of lesions on maxillofacial tissues, including medication-related osteonecrosis of the jaw, post-extraction wound healing, implant surgery, temporomandibular joint diseases, and periodontal tissue restoration.

Association between serum albumin and severe impairment of activities of daily living in patients with stroke: a cross-sectional study.

Purpose: The relationship between serum albumin levels and severe limitations in ADLs among stroke patients remains unclear. Specifically, the dose-response relationship between the two needs further exploration. This study aims to provide further results.

Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting mA Methylation-Dependent ATG5/Autophagy in Prostate Cancer.

This study aims to study how gold nanoparticles (AuNPs) function in the recruitment and polarization of tumor-associated macrophages (TAMs) in hormone-sensitive prostate cancer (HSPC) and castration-resistant prostate cancer (CRPC). Phorbol ester (PMA)-treated THP-1 cells were cocultured with LNCaP or PC3 cells to simulate TAMs. Macrophage M2 polarization levels were detected using flow cytometry and M2 marker determination.

Heavy Metal Distribution in Aquatic Products from Eastern Guangdong and Associated Health Risk Assessment.

With the rapid industrialization and urbanization of coastal areas, marine pollution (such as heavy metals) is increasingly contaminating the environment, posing significant public health risks. Eastern Guangdong, a key aquaculture and fisheries hub in China, has a growing market for aquatic products. Heavy metals persist in the environment and are difficult to degrade and bioaccumulate in marine organisms through the food web, presenting carcinogenic and mutagenic risks to humans, as top predators.