Influence of Aortic Deviation on Abdominal Aorta Bifurcation Level Relative to Vertebral Position.

Introduction Research on abdominal aortic deviation (AAD) and its impact on the vertebral level of abdominal aortic bifurcation (AAB) has been limited. We aimed to determine the level of AAB with respect to vertebral levels and assess the proportion of AAD and its impact on AAB. Materials and methods This single-arm, cross-sectional, retrospective study involved contrast-enhanced computed tomography (CECT) scans of the abdomen and pelvis of 208 subjects aged 18 years or older.

Real-world evidence in the cloud: Tutorial on developing an end-to-end data and analytics pipeline using Amazon Web Services resources.

In the rapidly evolving landscape of healthcare and drug development, the ability to efficiently collect, process, and analyze large volumes of real-world data (RWD) is critical for advancing drug development. This article provides a blueprint for establishing an end-to-end data and analytics pipeline in a cloud-based environment. The pipeline presented here includes four major components, including data ingestion, transformation, visualization, and analytics, each supported by a suite of Amazon Web Services (AWS) tools.

Con: indwelling pleural catheters cause harm to patients.

Indwelling pleural catheters (IPCs) have rapidly grown in popularity since their introduction for the management of recurrent pleural effusions. In malignant pleural effusions especially, there has been a shift away from measuring pleurodesis success and towards more patient-centred outcomes. Multiple randomised controlled trials have shown that despite lower rates of pleurodesis, symptom control and quality of life outcomes are comparable when compared to alternatives such as talc pleurodesis.

Associations between Chest Pain, Diagnosis, and Clinical Outcome in Patients Hospitalized with Acute Dyspnea: Data from the ACE 2 Study.

Introduction: Patients hospitalized due to dyspnea sometimes also report concomitant chest pain. Whether co-existing chest pain in patients with acute dyspnea associates with specific diagnosis and clinical outcome is not known.

Method: We included 313 patients admitted to Akershus University Hospital with acute dyspnea and asked the patients directly on hospital admission whether they had experienced chest pain during the last 24 h.

Re-inventing traditional aluminum-based adjuvants: Insight into a century of advancements.

Aluminum salt-based adjuvants like alum, alhydrogel and Adju-Phos are by far the most favored clinically approved vaccine adjuvants. They have demonstrated excellent safety profile and currently used in vaccines against diphtheria, tetanus, pertussis, hepatitis B, anthrax etc. These vaccinations cause minimal side effects like local inflammation at the injection site.