Publications by authors named "R Berretta"
Background: The intrauterine manipulator used during a hysterectomy for endometrial cancer has been suggested as a reason for worsening oncologic outcomes. However, only a few non-randomized retrospective studies have investigated this association.
Primary Objectives: To compare 4-year recurrence-free survival in the group of patients who undergo hysterectomy using an intrauterine manipulator with that of those who undergo hysterectomy without it.
Article Synopsis
- Endometriosis is a non-cancerous condition affecting women that may be linked to an increased risk of ovarian cancer, specifically certain types like endometrioid and clear cell subtypes.
- Atypical endometriosis (AE) shows unusual microscopic features that complicate its diagnosis, necessitating thorough histological evaluation to identify its distinct architectural and cytologic forms.
- Long-term studies indicate low rates of recurrence and malignancy in AE patients, but further research and interdisciplinary collaboration are essential to grasp the condition's cancer risk and improve diagnostic methods.
Objective: To investigate the safety of sentinel node mapping for patients with early-stage cervical cancer undergoing cervical conization plus nodal evaluation.
Methods: The ETERNITY project is a retrospective, multi-institutional study collecting data of patients with early-stage cervical cancer undergoing fertility-sparing treatment. Here, we compared outcomes related to three methods of nodal assessment: sentinel node mapping (SNM), SNM plus backup lymphadenectomy (SNM + LND); pelvic lymphadenectomy (LND).
Article Synopsis
- - This study analyzed data from 331 women with recurrent endometrial cancer to improve criteria for choosing candidates for secondary cytoreductive surgery, focusing on identifying preoperative predictors and assessing surgical complexity.
- - Key findings indicated that younger patients (under 65 years) with single-site relapses and fewer health complications were more likely to achieve complete tumor removal during surgery.
- - A new predictive scoring system was proposed based on the identified factors, showing potential for better patient selection for secondary cytoreductive surgery in this type of cancer.
Ovarian cancer (OC) remains a significant health challenge globally, with high mortality rates despite advancements in treatment. Emerging research suggests a potential link between OC development and genital dysbiosis, implicating alterations in the microbiome composition as a contributing factor. To investigate this correlation, a meta-analysis was conducted following PRISMA and MOOSE guidelines, involving eight studies encompassing 3504 patients.
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