Publications by authors named "R Bellmann-Weiler"
Coronavirus Disease 2019 causes significant morbidity, and different variants of concern (VOCs) can impact organ systems differently. We conducted a single-center retrospective cohort analysis comparing biomarkers and clinical outcomes in hospitalized patients infected with the wild-type or Alpha (wt/Alpha) VOC against patients infected with the Omicron VOC. We included 428 patients infected with the wt/Alpha VOC and 117 patients infected with the Omicron VOC.
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- Pneumonia, caused by viruses and bacteria, triggers both innate and adaptive immune responses, which can be measured through biomarkers like C-reactive protein (CRP) and Neopterin.
- A study involving 194 patients aimed to evaluate these biomarkers in differentiating between viral and bacterial pneumonia and to assess the occurrence of neuropsychiatric symptoms among patients.
- Results indicated that higher CRP/Neopterin ratios are linked to bacterial pneumonia, while lower ratios were found in COVID-19 and bacterial superinfections, successfully distinguishing between the types of pneumonia and indicating the presence of superinfections.
Research into the molecular basis of disease trajectory and Long-COVID is important to get insights toward underlying pathophysiological processes. The objective of this study was to investigate inflammation-mediated changes of metabolism in patients with acute COVID-19 infection and throughout a one-year follow up period. The study enrolled 34 patients with moderate to severe COVID-19 infection admitted to the University Clinic of Innsbruck in early 2020.
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- Seasonally circulating viruses, like Influenza and SARS-CoV-2 variants, highlight the need for affordable and effective antiviral medications.
- The study tested a natural essence called P80, derived from Dimocarpus longan, and found it effectively protected human airway cells from these viruses while reducing inflammation.
- P80 can be used as a nasal spray or lozenge, showing promise as a preventive treatment against respiratory infections, with lasting protective effects on tissue integrity and immune response.
Distinct smell and taste disorder phenotype of post-acute COVID-19 sequelae.
Eur Arch Otorhinolaryngol
November 2023
Purpose: Olfactory dysfunction (OD) commonly accompanies coronavirus disease 2019 (COVID-19). We investigated the kinetics of OD resolution following SARS-CoV-2 infection (wild-type and alpha variant) and its impact on quality of life, physical and mental health.
Methods: OD prevalence was assessed in an ambulatory COVID-19 survey (n = 906, ≥ 90 days follow-up) and an observational cohort of ambulatory and hospitalized individuals (n = 108, 360 days follow-up).