Publications by authors named "R Bekeredjian"
Article Synopsis
- Coronary functional disorders (CFD) significantly contribute to angina in patients with non-obstructed coronary arteries (ANOCA), with different endotypes identified, such as microvascular spasm and coronary microvascular dysfunction (CMD).
- A study involving 89 ANOCA patients using comprehensive coronary functional testing (CFT) found that 91% had at least one disorder, with microvascular spasm being the most common (61%).
- The results highlighted that isolated CMD is rare and emphasized the necessity of spasm testing for diagnosing and characterizing CFD in ANOCA patients.
Article Synopsis
- * The research involved 372 patients with angina but non-obstructive coronary arteries, comparing results from those who received RASP vs. those who did not during ACh provocation testing.
- * Findings indicated that RASP did not significantly change the frequency or type of coronary vasomotor responses when tested with ACh, meaning it can be safely used in patients undergoing spasm testing.
Background: Approximately 5-15% of patients with acute coronary syndrome have myocardial infarction with unobstructed coronary arteries (MINOCA). Guidelines recommend invasive assessments to identify underlying causes for MINOCA such as coronary artery spasm (CAS), spontaneous coronary dissection, or microvascular disease as well as non-invasive assessments in search of myocarditis, takotsubo syndrome, or cardiomyopathies.
Case Summary: A 54-year-old male patient presented with ST-segment elevation myocardial infarction (STEMI).
We present a case of a man in his 40s with pulmonary-renal syndrome due to myeloperoxidase-positive antineutrophil cytoplasmic antibodies-associated vasculitis and concurrent cold agglutinin disease, a combination that has not yet been described in the literature. The fulminant course of the disease, including the need for kidney replacement therapy and mechanical ventilation posed a significant treatment challenge due to haemolytic complications.
View Article and Find Full Text PDFMyocardial ischemia is a complex condition which may result from epicardial and/or microvascular causes involving functional and structural mechanisms. These mechanisms may overlap in a given patient illustrating the difficulties for appropriate management. Assessment of myocardial ischemia can be performed using noninvasive and invasive tools.
View Article and Find Full Text PDF