Publications by authors named "R Bedair"
Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.
View Article and Find Full Text PDFBackground: An individual's genetic fingerprint is emerging as a pivotal predictor of numerous disease- and treatment-related factors. Single nucleotide polymorphisms (SNPs) in drug-metabolizing enzymes play key roles in an individual's exposure to a malignancy-associated risk, such as Aflatoxin B1 (AFB1)-induced hepatocellular carcinoma (HCC).
Aim: This study aimed at reviewing literature on the polymorphisms that exist in CYP enzymes and their possible link with susceptibility to AFB1-induced HCC.
Article Synopsis
- The study focused on three species of the genus Solanum found in Egypt, which are morphologically similar, prompting the need for alternative identification methods.
- Researchers conducted anatomical, ecological, and molecular analyses, including DNA sequencing and gas chromatography-mass spectrometry (GC-MS) to characterize these species.
- Findings revealed variations in the anatomical features, molecular sequences, and chemical profiles of the species, with 38 compounds identified, aiding in their chemical identification.
Article Synopsis
- Postinfarct ventricular septal rupture poses a serious risk and has uncertain treatment timing and options due to lack of clinical trials.
- A new 36 mm Occlutech® device was successfully used on six patients with large ruptures who couldn't be treated with existing devices, marking its first human application.
- While the procedure showed immediate success and reduced shunts, half of the patients in cardiogenic shock did not survive, indicating a need for further device improvements to enhance outcomes.
Transthoracic echocardiography is an essential tool in the diagnosis, assessment, and management of paediatric and adult populations with suspected or confirmed congenital heart disease. Congenital echocardiography is highly operator-dependent, requiring advanced technical acquisition and interpretative skill levels. This document is designed to complement previous congenital echocardiography literature by providing detailed practical echocardiography imaging guidance on sequential segmental analysis, and is intended for implementation predominantly, but not exclusively, within adult congenital heart disease settings.
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