Publications by authors named "R Bechar"
Article Synopsis
- - Genome editing of human induced pluripotent stem cells (iPSCs) is crucial for research in genetics, disease studies, and regenerative medicine, but low efficiency in CRISPR-Cas9 methods has been a barrier due to high cell death after electroporation.
- - Introducing BCL-XL significantly boosts iPSC survival and enhances genome editing success, with increases of 20- to 100-fold in gene insertion efficiency and up to 5-fold in gene deletion success.
- - Further use of the BCL inhibitor ABT-263 improves editing efficiency even more, enabling near-perfect knockout rates and making extensive genetic modifications in cell populations easier without the need for time-consuming individual cell cloning.
Introduction: Stress fractures (SFs) occur when microdamage caused by repetitive mechanical load exceeds the biological load-bearing capacity of the bone. The study objective was to test whether a vest specifically designed and manufactured for female recruits, compared with the standard vest used on a regular basis by Border Police recruits, would reduce the incidence of SF in female Border Police recruits. Data based on reports of military personnel show that women are more likely to sustain SFs.
View Article and Find Full Text PDFIntroduction: Overuse pain syndromes constitute a troublesome byproduct of military infantry training, particularly in female fighters. These injuries result in lost days of training, pain and discomfort and can affect fitness and fighting abilities. We hypothesized that a gender specific vest would reduce the incidence of overuse pain syndromes in a population of female recruits during basic training.
View Article and Find Full Text PDFObjectives: This prospective, nationally representative, multi-centre study was undertaken to assess non-collision injuries sustained by public bus passengers in Israel.
Methods: The emergency departments (EDs) of six medical centres, which participated in this eight month study, were chosen to represent both urban and rural catchment areas. All patients diagnosed with injuries sustained on a public bus not involved in a road traffic accident were promptly evaluated for mechanism and nature of injury and demographic parameters.