A Comparative Study of ChatGPT and BingAI in Answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-Style Practice Questions: A Cross-Sectional Analysis.

Purpose: The integration of artificial intelligence (AI) into medical education has witnessed significant progress, particularly in the domain of language models. This study focuses on assessing the performance of two notable language models, ChatGPT and BingAI Precise, in answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-style practice questions, simulating medical exam formats.

Methods: A cross-sectional study conducted in June 2023 involved assessing ChatGPT and BingAI Precise using three sets of NEET-PG practice exams, comprising 200 questions each.

Effect of CFTR modulators Elexacaftor/Tezacaftor/Ivacaftor on lipid metabolism in human bronchial epithelial cells.

Cystic Fibrosis (CF) is a life-threatening hereditary disease resulting from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene that encodes a chloride channel essential for ion transport in epithelial cells. Mutations in CFTR, notably the prevalent F508del mutation, impair chloride transport, severely affecting the respiratory system and leading to recurrent infections. Recent therapeutic advancements include CFTR modulators such as ETI, a combination of two correctors (Elexacaftor and Tezacaftor) and a potentiator (Ivacaftor), that can improve CFTR function in patients with the F508del mutation.

Evaluation of French practices in the management and the follow-up of obstetric anal sphincter injuries (OASIS).

Objective: The aim was to assess the current management and follow-up of obstetric anal sphincter injuries in maternity wards in France at two levels: the patient's and the care unit level.

Study Design: We carried out an evaluation of professional practices in all French maternity hospitals by sending a questionnaire that covered five areas: (i) general information about the hospital, (ii) immediate management of OASIS and postpartum care, (iii) patient follow up, (iv) management of a subsequent pregnancy, and (v) training of health professionals.

Results: During this period, 102 answers (22.

Efficient DNA-free co-targeting of nuclear genes in Chlamydomonas reinhardtii.

Chlamydomonas reinhardtii, a model organism for unicellular green microalgae, is widely used in basic and applied research. Nonetheless, proceeding towards synthetic biology requires a full set of manipulation techniques for inserting, removing, or editing genes. Despite recent advancements in CRISPR/Cas9, still significant limitations in producing gene knock-outs are standing, including (i) unsatisfactory genome editing (GE) efficiency and (ii) uncontrolled DNA random insertion of antibiotic resistance markers.

Severe Central Nervous System and Respiratory Depression in a Neonate Following Accidental Oral Ingestion of Brimonidine Tartrate.

Brimonidine is a third-generation alpha-2 adrenergic agonist and is classified as an ocular hypotensive agent. It is used for chronic glaucoma treatment by lowering intraocular pressure, crucial for preventing blindness. Brimonidine works by reducing aqueous humor production and increasing uveoscleral outflow.