Digitising biopiracy? The global governance of plant genetic resources in the age of digital sequencing information.

Historical concerns over the exploitation of the Global South's genetic biodiversity framed the importance of creating global governance mechanisms to ensure fair access to and benefit-sharing of genetic resources worldwide. The Convention on Biological Diversity (CBD) and International Treaty on Plant Genetic Resources for Food and Agriculture (Plant Treaty) came into existence over the past three decades to redress the centuries of genetic exploitation of the Global South. Both of the treaties explicitly regulate and facilitate the exchange of physical genetic material.

Effect of substrate on the proliferation of Myxobolus cerebralis in the mitochondrial lineages of the Tubifex tubifex host.

The study goal was to examine the effects of sand and mud on the propagation of Myxobolus cerebralis, the whirling disease agent, in four mitochondrial 16S ribosomal DNA lineages (I, III, V, VI) of its oligochaete host, Tubifex tubifex (Tt). In all the lineage groups held continuously in either substrate (non-shifted) or transferred from sand to mud (shifted), substrate influenced parasite proliferation only in lineage III. Sporogenesis and release of triactinomyxon spores (TAMs) were more prevalent in lineage III Tt in mud compared to sand.

Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli.

Since antibiotic development lags, we search for potential drug targets through directed evolution experiments. A challenge is that many resistance genes hide in a noisy mutational background as mutator clones emerge in the adaptive population. Here, to overcome this noise, we quantify the impact of mutations through evolutionary action (EA).