Publications by authors named "R Barrera-Chacon"
Article Synopsis
- Leptospirosis is a serious bacterial infection in dogs that can lead to severe complications like pulmonary hemorrhagic syndrome (LPHS), and the study aims to understand certain blood ratio indicators in affected dogs.
- The study involved comparing 36 dogs with leptospirosis to 32 healthy control dogs, analyzing neutrophil to lymphocyte ratio (NLR), platelets to lymphocytes (PLR), and systemic immune-inflammation index (SII).
- Findings suggest that NLR significantly increased in infected dogs, while SII showed a notable difference in survivors, indicating NLR could serve as a marker for inflammation, but further research is needed on PLR and SII for canine leptospirosis.
Leishmaniasis is a zoonotic disease caused by Leishmania spp., impacts multiple systems and organs. While hematological and biochemical profiles aren't definitive for diagnosis, recent studies have identified the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) as predictors of morbidity and mortality in critically ill human and dog patients.
View Article and Find Full Text PDFThe objective of our study was to search for survival biomarkers (SB) and treatment response monitoring biomarkers (TRMB) in the urinary proteome of dogs with renal disease secondary to canine leishmaniosis (CanL), using UHPLC-MS/MS. The proteomic data are available via ProteomeXchange with identifier PXD042578. Initially, a group of 12 dogs was evaluated and divided into survivors (SG; n = 6) and nonsurvivors (NSG; n = 6).
View Article and Find Full Text PDFBackground: Myocarditis frequently occurs in canine leishmaniosis (CanL). Heart fatty acid-binding protein (HFABP) is a biomarker of myocardial damage.
Methods: This study aimed to compare HFABP concentration (HFABPc) in healthy dogs and dogs at different stages of CanL and evaluate the correlation of this biomarker with several clinicopathological and echocardiographic variables.
Canine leishmaniosis is frequently associated with the development of renal disease. Its pathogenesis is complex and not fully understood. For this reason, this study aimed to describe the urinary proteome, and identify possible new biomarkers in dogs with kidney disease secondary to leishmaniosis.
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