Publications by authors named "R Balestrino"

Introduction: Non-motor symptoms (NMS) in Parkinson's disease (PD) can fluctuate daily, impacting patient quality of life. The Non-Motor Fluctuation Assessment (NoMoFA) Questionnaire, a recently validated tool, quantifies NMS fluctuations during ON- and OFF-medication states. Our study aimed to validate the Italian version of NoMoFA, comparing its results to the original validation and further exploring its clinimetric properties.

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Background And Objectives: Editors of scientific journals play a key role in the health-related research process. Our study aims to characterize the demographics, work habits, decision-making processes, and ethical challenges faced by editors of neurological journals and to evaluate associations between editor or journal characteristics and editorial decisions, as well as sources of conflict of interest.

Methods: Cross-sectional study involving editors from neurological journals that fell above the 50th percentile in the Scimago rankings.

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Article Synopsis
  • The study looks at bradykinesia, which is when movement becomes slow and small, particularly in people with Parkinson's disease (pwPD) during a hand-tapping task.
  • Researchers compared 25 people with Parkinson's to 25 healthy controls using a brain scan and special gloves to measure their hand movements.
  • They found that people with Parkinson's had less movement and their brains showed different activity patterns, losing some coordination areas and using more cognitive areas instead, which helps understand how their movement problems happen.
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Background: Isolated rapid eye movement sleep behavioral disorder (iRBD) can precede neurodegenerative diseases. There is an urgent need for biomarkers to aid early intervention and neuroprotection.

Objective: The aim is to assess quantitative motor, cognitive, and brain magnetic resonance imaging (MRI) characteristics in iRBD patients.

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Background Whether connectome mapping of structural and functional connectivity across the brain could be used to predict patterns of atrophy progression in patients with mild Parkinson disease (PD) has not been well studied. Purpose To assess the structural and functional connectivity of brain regions in healthy controls and its relationship with the spread of gray matter (GM) atrophy in patients with mild PD. Materials and Methods This prospective study included participants with mild PD and controls recruited from a single center between January 2012 and December 2023.

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