Radiological features of brain hemorrhage through automated segmentation from computed tomography in stroke and traumatic brain injury.

Introduction: Radiological assessment is necessary to diagnose spontaneous intracerebral hemorrhage (ICH) and traumatic brain injury intracranial hemorrhage (TBI-bleed). Artificial intelligence (AI) deep learning tools provide a means for decision support. This study evaluates the hemorrhage segmentations produced from three-dimensional deep learning AI model that was developed using non-contrast computed tomography (CT) imaging data external to the current study.

Evaluation of β-Catenin Inhibition of Axitinib and Nitazoxanide in Human Monocyte-Derived Dendritic Cells.

Modulation of β-catenin signaling has attractive therapeutic potential in cancer immunotherapy. Several studies have found that β-catenin can mediate immune evasion in cancer and promote anti-inflammatory features of antigen-presenting dendritic cells. Many small molecular compounds that inhibit Wnt/β-catenin signaling are currently in clinical development, but none have entered routine clinical use.

Liquefaction of lignocellulosic biomass for methane production: A review.

Hydrothermal pretreatment (HTP) (Hot water extraction (HWE) and steam pretreatment) and pyrolysis have the potential to liquefy lignocellulosic biomass. HTP produces hydrolysate, consisting mainly of solubilized hemicellulose, while pyrolysis produces aqueous pyrolysis liquid (APL). The liquid products, either as main products or by-product, can be used as anaerobic digestion (AD) feeds, overcoming shortcomings of solid-state AD (SS-AD).

Dual Pro- and Anti-Inflammatory Features of Monocyte-Derived Dendritic Cells.

The transcription factor β-catenin is able to induce tolerogenic/anti-inflammatory features in different types of dendritic cells (DCs). Monocyte-derived dendritic cells (moDCs) have been widely used in dendritic cell-based cancer therapy, but so far with limited clinical efficacy. We wanted to investigate the hypothesis that aberrant differentiation or induction of dual pro- and anti-inflammatory features may be β-catenin dependent in moDCs.

Treatment of Metformin-Containing Wastewater by a Hybrid Vertical Anaerobic Biofilm-Reactor (HyVAB).

Several series of batch and continuous experiments were performed to investigate the removal of metformin and other contaminants from two wastewaters: wastewater I (WWI) containing 4 mg/L metformin and wastewater II (WWII) containing 110 g/L butanol. Biomethane potential (BMP) tests on WWII showed 77% of total chemical oxygen demand (tCOD = 110 g/L) degradability, and no apparent inhibition effects were observed. BMP tests on WWI showed an apparent inhibitory effect reflected in lower biogas production with increasing metformin concentration in the wastewater.